Transformation of Sib-Pair Values for the Haseman-Elston Method.

Authors :: Wang, Daolong
Lin, Shili
Cheng, Rong
Gao, Xin
Wright, Fred A.
Source :: American Journal of Human Genetics. May2001, Vol. 68 Issue 5, p1238. 12p. 4 Graphs.
Publication Year :: 2001
Abstract: Presents a study which examined the efficiency of sib-pair phenotype difference in Haseman-Elston regression compared to other proposed functions of the sibling-pair phenotypes. Four transformation schemes of sibling-pair values; Theoretical aspects of the transformation schemes; Applications to Genetic Analysis Workshop 10 data and additional simulations.