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Genetic factors underlie stability of obsessive-compulsive symptoms.
- Source :
-
Twin Research & Human Genetics . Oct2009, Vol. 12 Issue 5, p411-419. 9p. 2 Diagrams, 4 Charts. - Publication Year :
- 2009
-
Abstract
- The contribution of genetic and environmental factors to the stability of obsessive-compulsive (OC) symptoms has not yet been established in adult population based samples. We obtained the Young Adult Self Report Obsessive-Compulsive Subscale in mono- and dizygotic twins from the population-based Netherlands Twin Register in 1991, 1995 and 1997 and the Padua Inventory Revised Abbreviated in 2002. Stability of OC symptoms was analyzed as a function of genetic and environmental components. Heritability of OC behavior was around 40% at each time-point, independent of the instrument used. OC behavior was moderately stable with correlations ranging between r = .2 (for 11-year intervals), .4 (for 4-5 year intervals) and .6 (for 2 year intervals). Genetic correlations across time were higher, varying between .4 and .9, indicating that the stability of OC symptoms is mainly due to stable genetic factors. This study showed a moderate heritability and stability for OC behavior in adults. Genetic stability across time is high. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 18324274
- Volume :
- 12
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Twin Research & Human Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 44460631
- Full Text :
- https://doi.org/10.1375/twin.12.5.411