Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis.

Aims: In cells, mitochondria are organized as a network of interconnected organelles that fluctuate between fission and fusion events (mitochondrial dynamics). This process is associated with cell death. We investigated whether activation of apoptosis with ceramides affects mitochondrial dynamics and promotes mitochondrial fission in cardiomyocytes. [ABSTRACT FROM PUBLISHER]