Neutrophil Gelatinase—Associated Lipocalin Is a Predictor of the Course of Global and Renal Childhood-Onset Systemic Lupus Erythematosus Disease Activity.

The article examines the ability of neutrophil gelatinase-associated lipocalin (NGAL) to predict worsening of renal disease activity in childhood-onset systemic lupus erythematosus (SLE). It highlights a longitudinal prospective study which was conducted to 111 patients with childhood-onset SLE. According to the article, serial measurement of urinary and plasma NGAL levels can be important in the prediction of global renal SLE disease activity.