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SIRT1 Regulation of Apoptosis of Human Chondrocytes.
- Source :
-
Arthritis & Rheumatism . Sep2009, Vol. 60 Issue 9, p2731-2740. 10p. 6 Diagrams. - Publication Year :
- 2009
-
Abstract
- The article presents a study which aims to investigate the association of SIRT1, known to inhibit apoptosis, to apoptosis of human chondrocytes. It examines the expression of SIRT1 in human chondrocytes through reverse transcription-polymerase chain reaction and immunohistology of human cartilage samples. According to the study, SIRT1 regulates apoptosis in human chondrocytes by the modulation of mitochondria-associated apoptotic signals.
Details
- Language :
- English
- ISSN :
- 00043591
- Volume :
- 60
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Arthritis & Rheumatism
- Publication Type :
- Academic Journal
- Accession number :
- 44288276
- Full Text :
- https://doi.org/10.1002/art.24864