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Strand Invasion of Extended, Mixed-Sequence B-DNA by γPNAs.

Authors :
Gaofei He
Rapireddy, Srinivas
Bahal, Raman
Sahu, Bichismita
Ly, Danith H.
Source :
Journal of the American Chemical Society. 9/2/2009, Vol. 131 Issue 34, p12088-12090. 3p. 5 Graphs.
Publication Year :
2009

Abstract

The article presents a study on the ability of peptide nucleic acids (PNAs) to invade double-stranded DNA. The study intends to prove the ability of the direct Watson-Crick base pairing as an efficient method for strand invasion. It highlights that the direct Watson-Crick base only requires a single strand of PNA for invasion.

Details

Language :
English
ISSN :
00027863
Volume :
131
Issue :
34
Database :
Academic Search Index
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
44230176
Full Text :
https://doi.org/10.1021/ja900228j