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The relationship of oxidative stress and cholesterol with dipping status before and after aerobic exercise training.
- Source :
-
Blood Pressure . Aug2009, Vol. 18 Issue 4, p171-179. 9p. 3 Charts, 2 Graphs. - Publication Year :
- 2009
-
Abstract
- Objective. The purpose of this study was to examine the effects of aerobic exercise training (AEXT) on dipping status in pre-hypertensive and stage-1 hypertensive individuals. A secondary purpose was to evaluate whether AEXT alters oxidative stress and endothelial biomarkers correlated to dipping status. Methods. Twenty-three subjects underwent 24-h ambulatory blood pressure monitoring at baseline and after 6 months of AEXT. AEXT consisted of training at 70% VO2max 3 days/week for 6 months. Total cholesterol, high-density lipoprotein-cholesterol, low-density lipoprotein (LDL)-cholesterol, oxidized LDL (ox-LDL), triglycerides, urinary and plasma nitric oxide end-products, superoxide dismutase and 8-iso-PGF2α were measured before and after AEXT. Statistically, ANOVA and linear regression were used. Results. Before and after AEXT, there were no significant differences between dippers and non-dippers in any of the biomarkers except for total cholesterol following AEXT. In a sub-analysis following AEXT, 14 subjects retained their original dipping status, five subjects changed from dippers to non-dippers and four subjects changed from non-dippers to dippers. Significant differences existed between these groups in changes in total and LDL-cholesterol, ox-LDL, 8-iso-PGF2α and % Dip. Conclusions. Changes in cholesterol levels but not oxidative stress or endothelial biomarkers were related to changes in BP variables following AEXT in dippers and non-dippers. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08037051
- Volume :
- 18
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Blood Pressure
- Publication Type :
- Academic Journal
- Accession number :
- 43578582
- Full Text :
- https://doi.org/10.1080/08037050903047160