Modified Directly Observed Antiretroviral Therapy Compared With Self-administered Therapy in Treatment-Naïve HIV-1— Infected Patients: A Randomized Trial.

The article presents a study which examines the clinical effectiveness between modified directly observed therapy (mDOT) and Self-administered Therapy in human immunodeficiency virus (HIV) treatment. It examines whether this mDOT will be sustained after it was stopped. It reveals that mDOT is better than the latter within 6 months; however, their efficacy are not significantly different in a 1-year duration. It suggests that mDOT has marginal benefit and cannot be sustained after it was stopped.