El papel de la pérdida en la génesis de los trastornos depresivos.

Background. The role of loss has been carefully examined in research on depression, since it constitutes a central aspect of most of the life events that lead to depression. Methods. In the present study, a review of different studies on the role of loss was carried out, focusing on its different aspects and different types, the association between loss and some mental diseases, loss and prognosis, the relationship between hopelessness and loss, variations of the events of loss based on different factors, as well as loss in childhood. Results. Loss constitutes a central role in the appearance of many depressive disorders. It can act as a provoking agent, a vulnerability factor, or an agent that can modify the form, severity, and course of a depressive disorder. Different factors such as genetics, gender, or the time of life when the loss takes place can modulate the influence of loss events. [ABSTRACT FROM AUTHOR]