A high sensitivity time-resolved microfluorimeter for real-time cell biology.

Authors :: Martin-Fernandez, M.L.
Tobin, M.J.
Clarke, D.T.
Gregory, C.M.
Jones, G.R.
Source :: Review of Scientific Instruments. Oct96, Vol. 67 Issue 10, p3716. 6p. 3 Diagrams, 1 Chart, 3 Graphs.
Publication Year :: 1996
Abstract: Describes an instrument based on the novel combination of synchrotron radiation, a high sensitivity time-resolved microfluorimeter and a multiframe single photon counting data acquisition system. Design of the instrument to measure kinetic events in live cells using fluorescence resonance energy transfer; Ability to rapidly collect multiple consecutive decay profiles.