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Signaling Pathways Controlling Neural Stem Cells Slow Progressive Brain Disease.

Authors :
ANDROUTSELLIS-THEOTOKIS, A.
RUEGER, M. A.
MKHIKIAN, H.
KORB, E.
MCKAY, R. D. G.
Source :
Cold Spring Harbor Symposia on Quantitative Biology. 2008, Vol. 73, p403-410. 8p. 1 Diagram, 2 Graphs.
Publication Year :
2008

Abstract

The article discusses research being done on the relationship between stem cell survival and dopamine neurons and the effects of signaling pathways on the regeneration of brain diseases and in other tissues. The researchers discovered the interaction between insulin and Notch receptors to control the signaling cascade which is fundamental to cell growth. According to them, stem cell survival and dopamine neurons have regenerative effects in brain diseases.

Details

Language :
English
ISSN :
00917451
Volume :
73
Database :
Academic Search Index
Journal :
Cold Spring Harbor Symposia on Quantitative Biology
Publication Type :
Academic Journal
Accession number :
42838137
Full Text :
https://doi.org/10.1101/sqb.2008.73.018