Innate Factors in Human Breast Milk Inhibit Cell-Free HIV-1 but Not Cell-Associated HIV-1 Infection of CD4+ Cells.

The article focuses on a study which determines the impact of human breast milk on HIV infection and CD4+ cells replication. It also examines the ability of the breast milk to restrain HIV-1 transmission from infected CD4+ T lymphocytes. It reveals that breast milk has innate factors that protects against cell-free HIV-1. However, it has no capacity to block the transmission of cell-associated virus infection from HIV-infected CD4+ T lymphocytes to target cells.