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Isolation and characterization of a genotype 4 Hepatitis E virus strain from an infant in China.
- Source :
-
Virology Journal . 2009, Vol. 6, p1-4. 4p. 2 Diagrams. - Publication Year :
- 2009
-
Abstract
- In the present study, a genotype 4 HEV strain was identified in the fecal specimen from a seven months old infant with no symptom of hepatitis in Shanghai Children's hospital. The full capsid protein gene (ORF2) sequence of this strain was determined by RT-PCR method. Sequence analysis based on the full ORF2 sequence indicated that this HEV strain shared the highest sequence identity (97.6%) with another human HEV strain isolated from a Japanese patient who was infected by genotype 4 HEV during traveling in Shanghai. Phylogenetic analysis showed that this genotype 4 HEV was phylogenetically far from the genotype 4 HEV strain that was commonly prevalent in Shanghai swine group, suggesting that this strain may not come from swine group and not involved in zoonotic transmission in this area. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GENOTYPE-environment interaction
*HEPATITIS E
*GENE expression
*PHYLOGENY
*ZOONOSES
Subjects
Details
- Language :
- English
- ISSN :
- 1743422X
- Volume :
- 6
- Database :
- Academic Search Index
- Journal :
- Virology Journal
- Publication Type :
- Academic Journal
- Accession number :
- 42094626
- Full Text :
- https://doi.org/10.1186/1743-422X-6-24