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Antimitotic activity of lobaric acid and a new benzofuran, sakisacaulon A from Stereocaulon sasakii

Authors :
Morita, Hiroshi
Tsuchiya, Tomoe
Kishibe, Koji
Noya, Sayaka
Shiro, Motoo
Hirasawa, Yusuke
Source :
Bioorganic & Medicinal Chemistry Letters. Jul2009, Vol. 19 Issue 13, p3679-3681. 3p.
Publication Year :
2009

Abstract

Abstract: Lobaric acid (1) has been isolated from lichen, Stereocaulon sasakii together with a new benzofuran, sakisacaulon A (2). Lobaric acid (1) inhibited the polymerization of tubulin. Structure–activity relationship of lobaric acid and its derivatives on inhibitory activity of tubulin polymerization was discussed. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0960894X
Volume :
19
Issue :
13
Database :
Academic Search Index
Journal :
Bioorganic & Medicinal Chemistry Letters
Publication Type :
Academic Journal
Accession number :
41240893
Full Text :
https://doi.org/10.1016/j.bmcl.2009.03.170