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Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a...

Authors :
Tanner, Kirk G.
Landry, Joseph
Source :
Proceedings of the National Academy of Sciences of the United States of America. 12/19/2000, Vol. 97 Issue 26, p14178. 5p. 2 Diagrams, 9 Graphs.
Publication Year :
2000

Abstract

Investigates the enzymatic function of silent information regulator 2 (SIR2) protein family of NAD coenzyme-dependent histone-protein deacetylases. Reaction products; Proposed catalytic mechanisms for the production of 1-0-acetyl-ADP-ribose.

Details

Language :
English
ISSN :
00278424
Volume :
97
Issue :
26
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
4053970
Full Text :
https://doi.org/10.1073/pnas.250422697