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P53 Mutation in a Case of Blastic Transformation of Follicular Lymphoma with Double bcl-2....

Authors :
Nomdedeu, Josep F.
Source :
Leukemia & Lymphoma. May98, Vol. 29 Issue 5/6, p595. 11p. 3 Black and White Photographs, 2 Diagrams.
Publication Year :
1998

Abstract

Describes the p53 mutation in a case of blastic transformation of follicular lymphoma (FL) with double bcl-2 rearrangement. Description of a third breakpoint at the 5' part of the bcl-2 locus; Molecular analysis of an FL transformed into a blastic phase unresponsive to chemotherapy; Overexpression of p53 and bcl-2 on the affected sites.

Subjects

Subjects :
*P53 antioncogene
*LYMPHOMAS

Details

Language :
English
ISSN :
10428194
Volume :
29
Issue :
5/6
Database :
Academic Search Index
Journal :
Leukemia & Lymphoma
Publication Type :
Academic Journal
Accession number :
4019299