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Energetics of the Induced Structural Change in a Ca[sup 2+] Regulatory Protein: Ca[sup 2+] and....

Authors :
McKay, Ryan T.
Saltibus, Linda F.
Source :
Biochemistry. 10/17/2000, Vol. 39 Issue 41, p12731. 8p. 11 Diagrams, 2 Charts, 1 Graph.
Publication Year :
2000

Abstract

Examines the regulatory domains of skeletal and cardiac troponin C (sNTnC and cNTnC) upon calcium binding. Implication of E41A mutant enzyme for the calcium binding affinity of site I in sNTnC; Interaction between E41A-sNTnC with troponin I regions; Mechanism of the coupling of ligand binding involved in muscle contraction.

Subjects

Subjects :
*MUSCLE proteins
*CALCIUM

Details

Language :
English
ISSN :
00062960
Volume :
39
Issue :
41
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
3858300
Full Text :
https://doi.org/10.1021/bi001240u