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Genetic mosaic analysis based in Cre recombination and navigated laser capture...

Authors :
Wong, Melissa H.
Saam, Jennifer R.
Source :
Proceedings of the National Academy of Sciences of the United States of America. 11/07/2000, Vol. 97 Issue 23, p12601. 6p. 12 Color Photographs, 5 Diagrams, 3 Graphs.
Publication Year :
2000

Abstract

Presents an approach for conducting pathogenesis of mosaic diseases based on patterns of Cre recombinase protein expression in intestinal epithelium and laser capture microdissection. Utilization of transcriptional regulatory elements that direct region-specific and mosaic patterns; Method for retrieval of epithelial cells from crypts with or without recombination.

Details

Language :
English
ISSN :
00278424
Volume :
97
Issue :
23
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
3855820
Full Text :
https://doi.org/10.1073/pnas.230237997