Regulation of protein kinase C...I by two protein-tyrosine kinases, Btk and Syk.

Describes a study which provides genetic, biochemical and pharmacological evidence that, on high-affinity immunoglobulin receptors stimulation, Syk regulates Bruton's tyrosine kinase (Btk), and Btk regulates the membrane translocation and enzymic activity of protein kinase C. Cell culture and stimulation; Immunoblotting analysis and antibodies; Results and discussion.