Factor V 1691 G-A mutation distribution in a healthy Turkish population.

The aim of this review was to compile published data on factor V 1691 G-A alteration in a healthy Turkish population and also to stimulate the reporting of unpublished data, in order to create a map for factor V Leiden (FVL) in Turkey. From a total of 4276 healthy individuals from 26 different centers of Turkey, 345 FVL carriers (7.9%) were determined. FVL was strikingly high among newborns from two different centers (10.9%). [ABSTRACT FROM AUTHOR]