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Role of Immunogenic Fetuin A on L5178Y-R Lymphoma Tumorigenesis.
- Source :
-
Cancer Investigation . May2009, Vol. 27 Issue 3, p257-263. 7p. 3 Graphs. - Publication Year :
- 2009
-
Abstract
- In the present study, we report the detection of immunogenic fetuin-A on L5178Y-R (LY-R) lymphoma cells. Fetuin-A was recognized by antibodies present in the serum of LY-R tumor-bearing and immunized mice, but not by sera of mice immunized with the non-tumorigenic variant LY-S or by healthy mouse sera. However, according with Western blot analysis with commercial anti-fetuin antibodies, fetuin-A is present in both cell types which suggests that the fetuin recognized by anti-LY-R antibodies is an immunogenic form associated only with the tumorigenic LY-R cells and might be involved in tumor progression in this lymphoma. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 07357907
- Volume :
- 27
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Cancer Investigation
- Publication Type :
- Academic Journal
- Accession number :
- 37140337
- Full Text :
- https://doi.org/10.1080/07357900802337209