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Chlorination of Aniline and Methyl Carbanilate by N-Chlorosuccinimide and Synthesis of 1,3,5-Trichlorobenzene.

Authors :
Davis, MatthewC.
Source :
Synthetic Communications. 2009, Vol. 39 Issue 6, p1100-1108. 9p. 4 Diagrams.
Publication Year :
2009

Abstract

Aniline undergoes regioselective trichlorination by N-chlorosuccinimide (NCS) in acetonitrile in good yield. The product 2,4,6-trichoroaniline was converted into 1,3,5-trichlorobenzene by reduction of its diazonium salt. Reaction of the methyl carbamate of aniline with NCS gave only the 2,4-dichlorophenyl carbamate. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397911
Volume :
39
Issue :
6
Database :
Academic Search Index
Journal :
Synthetic Communications
Publication Type :
Academic Journal
Accession number :
36635361
Full Text :
https://doi.org/10.1080/00397910802499542