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Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function arid Human Diseases.

Authors :
Turgeon, Benjamin
Meloche, Sylvain
Source :
Physiological Reviews. Jan2009, Vol. 89 Issue 1, p1-26. 26p. 4 Diagrams, 3 Charts, 8 Graphs.
Publication Year :
2009

Abstract

The article discusses the study which examines the neonatal lethal phenotypes in mouse mutants. It investigates gene mutations leading to neonatal lethality and discusses the impact of these mutations on the major physiological processes critical to mouse newborn survival including parturition, breathing and homeostasis. Information related to the methods and outcomes of the study is further discussed.

Details

Language :
English
ISSN :
00319333
Volume :
89
Issue :
1
Database :
Academic Search Index
Journal :
Physiological Reviews
Publication Type :
Academic Journal
Accession number :
36238876
Full Text :
https://doi.org/10.1152/physrev.00040.2007