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Multiplexed genotyping of ABC transporter polymorphisms with the Bioplex suspension array.

Authors :
Seok Hwee Koo
Tan Ching Ong
Kok Ting Chong
Guat Lay Lee, Caroline
Fook Tim Chew
Jon Deoon Lee, Edmund
Source :
Biological Procedures Online. 2008, Vol. 10 Issue 1, p27-42. 16p. 1 Diagram, 7 Charts, 2 Graphs.
Publication Year :
2008

Abstract

The article discusses a study on the development of a consolidated bead-based genotyping platform, the Bioplex suspension array for simultaneous detection of multiple single nucleotide polymorphisms (SNPs) of the ATP-binding cassette transporters. It cites the influence of genetic polymorphisms on therapeutic response and risk of disease pathologies. The study concluded that the suspension array thus proves to be a reliable, cost-effective and high-throughput technological platform for genotyping.

Details

Language :
English
ISSN :
14809222
Volume :
10
Issue :
1
Database :
Academic Search Index
Journal :
Biological Procedures Online
Publication Type :
Academic Journal
Accession number :
36171635
Full Text :
https://doi.org/10.1251/bpo131