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Novel Wnt antagonists target porcupine and Axin.
- Source :
-
Nature Chemical Biology . Feb2009, Vol. 5 Issue 2, p74-75. 2p. 1 Diagram. - Publication Year :
- 2009
-
Abstract
- The article offers information on the small molecules that inhibit Wnt signaling by two mechanisms, giving a chance for research to improve treatment of colon cancer. It is said that Wnt signaling pathway has a role in the embryonic development. It is cited that nonsteroidal anti-inflammatory drugs (NSAIDs) have been known to inhibit Wnt signaling.
Details
- Language :
- English
- ISSN :
- 15524450
- Volume :
- 5
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Nature Chemical Biology
- Publication Type :
- Academic Journal
- Accession number :
- 36113372
- Full Text :
- https://doi.org/10.1038/nchembio0209-74