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JBIR-23 and -24, Novel Anticancer Agents from Streptomycessp. AK-AB27.
- Source :
-
Organic Letters . Jan2009, Vol. 11 Issue 2, p285-288. 4p. - Publication Year :
- 2009
-
Abstract
- The screening for active compounds against malignant pleural mesothelioma (MPM) cells produced by Streptomycessp. AK-AB27 resulted in the isolation of two compounds with a dodecahydrodibenzo[b,d]furan skeleton named JBIR-23 (1) and -24 (2). Their structures were established on the basis of extensive NMR and MS analyses. Compounds 1and 2exhibited cytotoxic effects against several MPM cell lines. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 11
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 36040001
- Full Text :
- https://doi.org/10.1021/ol802611w