Synthesize and characterization of organic-soluble acylated chitosan

Abstract: Acylated chitosan was synthesized by reaction of chitosan and stearoyl chloride. The chemical structures and physical properties of the prepared compounds were confirmed by Fourier transform infrared (FT-IR), 1H Nuclear Magnetic Resonance (1H NMR) spectroscopy, X-ray diffraction (XRD) and Thermogravimetric (TG) techniques. The degree of substitution (DS) was calculated by 1H NMR and ranged from 1.8 to 3.8. The synthesized compounds exhibited an excellent solubility in organic solvents. XRD analysis showed that they had high crystalline structure. TG results demonstrated that thermal stability of the prepared compounds was lower than that of chitosan, the weight loss decreased with increase of DS. This procedure could be a facile method to prepare organic-soluble chitosan derivatives. [Copyright &y& Elsevier]