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Dynamic Selection of Novel Vancomycin N-Terminal Derivatives by Resin-bound Reversed d-Ala-d-Ala.
- Source :
-
Journal of Combinatorial Chemistry . Oct2008, Vol. 10 Issue 6, p914-922. 9p. - Publication Year :
- 2008
-
Abstract
- The most attractive advantage of dynamic combinatorial chemistry (DCC) is that it can screen the compound library as soon as compounds are synthesized. However, it is very difficult to analyze a dynamic combinatorial library with free probes using the state-of-the art analysis technologies. We report herein a method that uses a resin-immobilizing reversed peptide probe to screen vancomycin derivatives and provides a solution to this problem. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15204766
- Volume :
- 10
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Journal of Combinatorial Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 35167610
- Full Text :
- https://doi.org/10.1021/cc800104b