Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6.

The article provides information on the research study entitled, "Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6." Skeletal muscle is now considered as part of the endocrine system because it secretes and excretes myokines. The first studied myokine is the gp130 receptor cytokines interleukin-6 (IL-6). IL-6 was found out to be a myokine because its amount increase by 100 times during physical exercise. Here, the mechanisms and roles of IL-6 in the human body are discussed.