Stressor-induced changes to the protoscoleces of Echinococcus granulosusof Indian buffalo origin.

AbstractIn the present study viable protoscoleces of Echinococcus granulosuswere exposed to in vitroanthelmintic treatment to observe efficacy against Indian buffalo isolates. Evaluation criteria included morphological changes, viability scores and expression of peptides as a product of prestressed protoscoleces. Protoscolex changes included presence of bladder-like structure and morphological distortion. Two peptides of relative molecular weight (Mr) 40 and 70?kDa were visualized when proteins were separated by discontinuous gel electrophoresis. These two peptides seemed to be products of prestressed protoscoleces. [ABSTRACT FROM AUTHOR]