Back to Search
Start Over
Substrate-Controlled Selective Proximal and Distal C—C Bond Cleavage via Lewis Acid Mediated O-Acylation of 2-(Arylmethylene)cyclopropylaldehyde: A Stereoselective Synthesis of Bifunctional Methylenecyclobutanes and 1,3-Conjugated Dienes.
- Source :
-
Journal of Organic Chemistry . 9/5/2008, Vol. 73 Issue 17, p6884-6887. 4p. 1 Diagram, 3 Charts. - Publication Year :
- 2008
-
Abstract
- ZnCl2-mediated reactions of (E)-2-(arylmethylene)cyclopropylaldehyde 1 with various acyl chlorides provide a novel method for stereoselective synthesis of bifunctional methlylenecyclobutanes via a proximal-bond cleavage process. Nevertheless, when (Z)-1 was employed, the reactions give 1,3-conjugated dienes through distal-bond cleavage. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00223263
- Volume :
- 73
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 34543099
- Full Text :
- https://doi.org/10.1021/jo801021f