Novelty seeking modulates medial prefrontal activity during the anticipation of emotional stimuli

Abstract: In a functional magnetic resonance imaging experiment, expectancy cues signaling emotional stimuli were used to study the personality trait of novelty seeking. BOLD responses to emotional expectancy were positively correlated with novelty-seeking scores in the medial prefrontal cortex. This correlation was strongest for the sub-dimension of exploratory excitability. [Copyright &y& Elsevier]