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Does epilepsy occur more frequently in children with Type 1 diabetes?
- Source :
-
Journal of Paediatrics & Child Health . Oct2008, Vol. 44 Issue 10, p586-589. 4p. 1 Chart. - Publication Year :
- 2008
-
Abstract
- Aim: Hypoglycaemic seizures are common in children with diabetes and electroencephalogram abnormalities are well recognised in this patient group. Elevated antibodies to glutamic acid decarboxylase, a major auto-antigen in Type 1 diabetes, are also implicated in a number of neurological disorders. Despite these associations, the question of whether children with diabetes are more prone to epilepsy, possibly as a result of lowered seizure threshold, has not been previously studied. We aimed to determine the prevalence and type of epilepsy in a large paediatric diabetes clinic. Methods: An audit by chart review was carried out at the Diabetes Clinic at the Royal Children's Hospital, Melbourne, Australia. Clinical, demographical, biochemical, EEG and neuro-imaging data were recorded. Results: Of 1384 children and adolescents aged 0–19 years with Type 1 diabetes, we identified 12 with active epilepsy (prevalence of 8.7/1000), the majority of whom had idiopathic generalised epilepsy and benign focal epilepsy of childhood. These findings are similar to those in the general population. Conclusion: Childhood epilepsy is no more frequently encountered in children and adolescents with Type 1 diabetes than in the general paediatric population. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10344810
- Volume :
- 44
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Journal of Paediatrics & Child Health
- Publication Type :
- Academic Journal
- Accession number :
- 34479587
- Full Text :
- https://doi.org/10.1111/j.1440-1754.2008.01387.x