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Short gamete co-incubation during in vitro fertilization decreases the fertilization rate and does not improve embryo quality: a prospective auto controlled study.
- Source :
-
Journal of Assisted Reproduction & Genetics . Jul2008, Vol. 25 Issue 7, p305-310. 6p. 1 Diagram, 2 Charts. - Publication Year :
- 2008
-
Abstract
- Purpose Evaluate the effect of short gamete incubation on fertilization rate and embryo quality. Methods A prospective study has been performed. Two thousand five hundred and forty seven sibling oocytes from 240 couples undergoing IVF attempts were allocated to a short (1 h) or a standard (18 h) insemination procedure. Diploid fertilization rate (two pronuclei, 2PN), polyspermy (>2PN) and embryo quality were compared. Results The fertilization rate was statistically lower in the short insemination group compared to the standard insemination one (64.9% and 70.1%; P=0.039), with a similar polyspermy rate observed between the two groups. A slight, but non significant, increase was observed concerning good embryo quality rate in the short insemination group when compared to the standard insemination, both at day 2 (60.1 vs. 58.1%; P=0.06) and day 3 (53.2 vs. 48.5%; P=0.22). Conclusion This new study highlights that a 1 h gamete exposure decreases the fertilization rate and does not improve embryo quality compared with a standard 18 h insemination procedure. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10580468
- Volume :
- 25
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Journal of Assisted Reproduction & Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 34462586
- Full Text :
- https://doi.org/10.1007/s10815-008-9240-3