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Robust Predictive Control Strategy Applied for Propofol Dosing Using BIS as a Controlled Variable During Anesthesia.
- Source :
-
IEEE Transactions on Biomedical Engineering . Sep2008, Vol. 55 Issue 9, p2161-2170. 10p. 6 Black and White Photographs, 3 Diagrams, 2 Charts, 10 Graphs. - Publication Year :
- 2008
-
Abstract
- This paper presents the application of predictive control to drug dosing during anesthesia in patients undergoing surgery. The performance of a generic predictive control strategy in drug dosing control, with a previously reported anesthesia-specific control algorithm, has been evaluated. The robustness properties of the predictive controller are evaluated with respect to inter- and intrapatient variability. A single-input (propofol) single-output (bispectral index, BIS) model of the patient has been assumed for prediction as well as for simulation. A set of 12 patient models were studied and interpatient variability and disturbances are used to assess robustness of the controller. Furthermore, the controller guarantees the stability in a desired range. The applicability of the predictive controller in a real-life environment via simulation studies has been assessed. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00189294
- Volume :
- 55
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- IEEE Transactions on Biomedical Engineering
- Publication Type :
- Academic Journal
- Accession number :
- 34299908
- Full Text :
- https://doi.org/10.1109/TBME.2008.923142