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THE PROMISE ON PHAGE DISPLAY: Customized Affinity and Specificity.
- Source :
-
Analytical Chemistry . 5/1/2008, Vol. 80 Issue 9, p3082-3089. 8p. - Publication Year :
- 2008
-
Abstract
- The article discusses phage display mechanisms and phage-based biosensors. Topics include the: advantages of using the bacteriophage called filamentous phage; manipulation of polypeptides on virus particle surfaces; selection of a polypeptide receptor and affinity screening; methods for immobilizing filamentous phage on biosensor surfaces; antibody binding on a covalent virus surface; prostate-specific membrane antigen--a cancer biomarker; biosensor transducer--electrochemical impedance spectroscopy; and binding of target molecules to macroscopic gold electrodes.
Details
- Language :
- English
- ISSN :
- 00032700
- Volume :
- 80
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Analytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 33750806
- Full Text :
- https://doi.org/10.1021/ac086009h