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Immunogenicity, safety and consistency of new trivalent inactivated influenza vaccine
- Source :
-
Vaccine . Jul2008, Vol. 26 Issue 32, p4057-4061. 5p. - Publication Year :
- 2008
-
Abstract
- Abstract: To augment the available influenza vaccine supply, a phase III study was conducted to evaluate the immunogenicity, safety, and consistency of a new trivalent inactivated influenza vaccine manufactured by CSL Limited. Healthy adults (ages 18–64) were randomized to receive either a single dose of TIV from multi-dose vials with thimerosal, TIV from pre-filled syringes without thimerosal, or placebo. Of the TIV recipients, 97.8% achieved a post-vaccination titer ≥40 against H1N1, 99.9% against H3N2 component, and 94.2% against influenza B. Few local or systemic adverse events were noted after vaccination with either TIV presentation. TIV was well tolerated and immunogenic. [Copyright &y& Elsevier]
- Subjects :
- *INFLUENZA vaccines
*INFLUENZA viruses
*PLACEBOS
*VACCINATION
Subjects
Details
- Language :
- English
- ISSN :
- 0264410X
- Volume :
- 26
- Issue :
- 32
- Database :
- Academic Search Index
- Journal :
- Vaccine
- Publication Type :
- Academic Journal
- Accession number :
- 33345310
- Full Text :
- https://doi.org/10.1016/j.vaccine.2008.05.024