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Total Synthesis of Crisamicin A.

Authors :
Zhengtao Li
Yingxiang Gao
Yefeng Tang
Mingji Dai
Guoxin Wang
Zhigang Wang
Zhen Yang
Source :
Organic Letters. May2008, Vol. 10 Issue 14, p3017-3020. 4p.
Publication Year :
2008

Abstract

Stereoselective total synthesis of natural product crisamicin A ( 1) was accomplished for the first time via the Pd/TMTU-catalyzed alkoxycarbonylative annulation to generate a unique cis-pyran-fused lactone, an intermolecular Diels−Alder reaction to construct the pyranonaphthoquinone unit, and a novel Pd−thiourea pincer complex-catalyzed homocoupling of functionalized naphthoquinones. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15237060
Volume :
10
Issue :
14
Database :
Academic Search Index
Journal :
Organic Letters
Publication Type :
Academic Journal
Accession number :
33200792
Full Text :
https://doi.org/10.1021/ol800977n