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Review of molecular modification techniques for improved detection of biomolecules by mass spectrometry
- Source :
-
Analytica Chimica Acta . Aug2008, Vol. 623 Issue 1, p1-10. 10p. - Publication Year :
- 2008
-
Abstract
- Abstract: After a soft ionizing method was established, MS (mass spectrometry) has become a more common tool in biochemistry because soft ionization made it possible to detect large molecules such as proteins. Many kinds of applications were established to further utilize MS for the identification or quantitation of biomolecules. In this review, we introduce recent applications with special focus on chemical modification techniques and chemical probes developed for the MS determination of biomolecules. [Copyright &y& Elsevier]
- Subjects :
- *MASS spectrometry
*BIOMOLECULES
*SPECTRUM analysis
*NUCLEAR spectroscopy
Subjects
Details
- Language :
- English
- ISSN :
- 00032670
- Volume :
- 623
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Analytica Chimica Acta
- Publication Type :
- Academic Journal
- Accession number :
- 32982995
- Full Text :
- https://doi.org/10.1016/j.aca.2008.05.064