Microwave-assisted solid acid-catalyzed one-pot synthesis of isobenzofuran-1(3H)-ones

Authors :: Landge, Shainaz M.
Berryman, Martin
Török, Béla
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jul2008, Vol. 49 Issue 29/30, p4505-4508. 4p.
Publication Year :: 2008
Abstract: Abstract: A new, solid acid-catalyzed microwave-assisted environmentally benign synthesis of isobenzofuran-1(3H)-ones is described. Montmorillonite K-10 appeared to be an excellent catalyst for the condensation and successive lactonization reactions. Reaction of phthalaldehydic acid (2-carboxybenzaldehyde) with methylaryl and cyclic ketones was initiated by microwave irradiation and occurred in one step. The reactions were complete in 10–30 minutes providing excellent yields (90–98%). [Copyright &y& Elsevier]

Language :: English
ISSN :: 00404039
Volume :: 49
Issue :: 29/30
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 32639243
Full Text :: https://doi.org/10.1016/j.tetlet.2008.05.068

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