Back to Search Start Over

Effect of Rifampicin on Lopinavir Pharmacokinetics in HIV-lnfected Children With Tuberculosis.

Authors :
Yuan Ren
Nuttall, James J. C.
Egbers, Claire
Eley, Brian S.
Meyers, Tammy M.
Smith, Peter J.
Maartens, Gary
McIlleron, Helen M.
Source :
JAIDS: Journal of Acquired Immune Deficiency Syndromes. 4/15/2008, Vol. 47 Issue 5, p566-569. 4p. 1 Chart, 1 Graph.
Publication Year :
2008

Abstract

The article reports on results of a study of the effect of rifampicin on lopinavir pharmacokinetics in HIV-infected children with tuberculosis. A description of the study design and methods is presented. The study showed that the effect of rifampicin-based antitubercular treatment on lopinavir concentrations was attenuated by adding ritonavir to rifampicin.

Details

Language :
English
ISSN :
15254135
Volume :
47
Issue :
5
Database :
Academic Search Index
Journal :
JAIDS: Journal of Acquired Immune Deficiency Syndromes
Publication Type :
Academic Journal
Accession number :
32595837
Full Text :
https://doi.org/10.1097/QAI.0b013e3181642257