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The Additive Genetic Gamma Frailty Model.
- Source :
-
Scandinavian Journal of Statistics . Jun98, Vol. 25 Issue 2, p255. 15p. 2 Diagrams. - Publication Year :
- 1998
-
Abstract
- ABSTRACT. In this paper the additive genetic gamma frailty model is defined. Individual frailties are correlated as a result of an additive genetic model. An algorithm to construct additive genetic gamma frailties for any pedigree is given so that the variance-covariance structure among individual frailties equals the numerator relationship matrix times a variance. The EM algorithm can be used to estimate the parameters in the model. Calculations are similar using the EM algorithm in the shared frailty model, however the E step is not correspondingly simple. This is illustrated re-analysing data, analysed by the shared frailty model in Nielsen et al. (1992), from the Danish adoptive register(*). Goodness of fit of the additive genetic gamma frailty model can be tested after analysing data with the correlated frailty model. Doing so, a "defect" in the often used and otherwise well behaving likelihood was found. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RANDOM walks
*ALGORITHMS
*GAMMA functions
Subjects
Details
- Language :
- English
- ISSN :
- 03036898
- Volume :
- 25
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Scandinavian Journal of Statistics
- Publication Type :
- Academic Journal
- Accession number :
- 3252598
- Full Text :
- https://doi.org/10.1111/1467-9469.00102