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IRAK-4 inhibitors. Part 1: A series of amides

Authors :
Buckley, George M.
Gowers, Lewis
Higueruelo, Alicia Perez
Jenkins, Kerry
Mack, Stephen R.
Morgan, Trevor
Parry, David M.
Pitt, William R.
Rausch, Oliver
Richard, Marianna D.
Sabin, Verity
Fraser, Joanne L.
Source :
Bioorganic & Medicinal Chemistry Letters. Jun2008, Vol. 18 Issue 11, p3211-3214. 4p.
Publication Year :
2008

Abstract

Abstract: The synthesis and profile of a series of amides are described. Some of these compounds were potent IRAK-4 inhibitors and two examples were evaluated in vivo. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0960894X
Volume :
18
Issue :
11
Database :
Academic Search Index
Journal :
Bioorganic & Medicinal Chemistry Letters
Publication Type :
Academic Journal
Accession number :
32494070
Full Text :
https://doi.org/10.1016/j.bmcl.2008.04.058