Effect of excimer laser repetition rate on outcomes after photorefractive keratectomy

Purpose: To compare the refractive outcomes after photorefractive keratectomy (PRK) for low to moderate myopic corrections using 2 excimer lasers with different repetition rates (200 Hz and 400 Hz). Setting: University refractive surgery center. Methods: This retrospective study included all consecutive patients who underwent PRK using the 200 Hz or the 400 Hz Allegretto laser platform (WaveLight Laser Technologie AG). Thirty-five patients (70 eyes) and 29 patients (58 eyes) had PRK with the 200 Hz platform and the 400 Hz platform, respectively, using the same surgical technique. Results: The mean follow-up was 13.22 months ± 1.16 (SD) (range 11 to 15 months). No intraoperative or early postoperative (eg, late reepithelialization) complications were found in either group. At 1 year, 66 eyes (94.2%) in the 200 Hz group and 56 eyes (96.6%) in the 400 Hz group were within ±1.00 diopter of the attempted correction. At 3 months, 20 eyes (29%) in the 200 Hz group and 27 eyes (46%) in the 400 Hz group had mild or moderate corneal haze (P = .03). These corneas showed progressive clearing over subsequent months without statistically significant differences in haze formation between the 2 groups. Twelve months after PRK, all corneas in both groups were clear. Conclusion: Photorefractive keratectomy for the treatment of low to moderate refractive errors using a 200 Hz or 400 Hz excimer laser gave comparable results. [Copyright &y& Elsevier]