Radical–polar crossover domino reactions involving organozinc reagents and β-(allyloxy)-enoates

Authors :: Giboulot, Steven
Pérez-Luna, Alejandro
Botuha, Candice
Ferreira, Franck
Chemla, Fabrice
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jun2008, Vol. 49 Issue 25, p3963-3966. 4p.
Publication Year :: 2008
Abstract: Abstract: Organozinc reagents (organozinc halides, diorganozincs and mixed copper–zinc reagents) react with β-(allyloxy)-enoates via a radical–polar crossover process to afford substituted furans in one single synthetic step following a domino reaction involving Michael addition and carbocyclisation. Reversal of diastereoselectivity can be obtained varying the organometallic and/or the reaction conditions. [Copyright &y& Elsevier]

Language :: English
ISSN :: 00404039
Volume :: 49
Issue :: 25
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 32073572
Full Text :: https://doi.org/10.1016/j.tetlet.2008.04.108

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