Comparative effectiveness of angiotensin-converting-enzyme inhibitors: Is an ACE always an ace?

The article relates the authors' perspective on the comparative effectiveness study of angiotensin-converting-enzyme (ACE) inhibitors in the treatment of congestive heart failure, published within the issue. They assert that the results of the study suggests that there maybe critical differences in outcomes among the groups of ACE inhibitors commonly used to treat heart failure. However, they argue that further studies are needed to compare ACE's efficacy and validate the study's findings.