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Combined Structural and Biochemical Analysis of the H-T Complex in the Glycine Decarboxylase...

Authors :
Guilhaudis, Laure
Simorre, Jean-Pierre
Source :
Biochemistry. 04/18/2000, Vol. 39 Issue 15, p4259. 8p. 4 Diagrams, 9 Graphs.
Publication Year :
2000

Abstract

Investigates the effect of the presence of the T-protein on the stability of methylamine-loaded H-protein. Indication that the role of the T-protein is not only to locate the tetrahydrofolate cofactor in a position favorable for a nucleophilic attack on the methylene carbon but also to destabilize the H-protein.

Subjects

Subjects :
*PROTEINS
*METHYLAMINES

Details

Language :
English
ISSN :
00062960
Volume :
39
Issue :
15
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
3174140
Full Text :
https://doi.org/10.1021/bi992674w