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2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: Optimization via array synthesis
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Apr2008, Vol. 18 Issue 8, p2640-2644. 5p. - Publication Year :
- 2008
-
Abstract
- Abstract: 2-Arylbenzoxazole 5 was identified as a hit from a fluorescence-based high-throughput screen for CETP inhibitors. The synthesis and SAR investigation employing array synthesis of the A- and B-rings are described. [Copyright &y& Elsevier]
- Subjects :
- *LUMINESCENCE
*RADIOACTIVITY
*RADIATION
*FLUORESCENCE
Subjects
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 18
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 31677410
- Full Text :
- https://doi.org/10.1016/j.bmcl.2008.03.030