Back to Search
Start Over
Technical note: The calibration of 90Y-labeled SIR-Spheres® using a nondestructive spectroscopic assay.
- Source :
-
Medical Physics . Apr2008, Vol. 35 Issue 4, p1278-1279. 2p. - Publication Year :
- 2008
-
Abstract
- 90Y-labeled SIR-Spheres® are currently used to treat patients with hepatic metastases secondary to colorectal adenocarcinoma. In general, the prescribed activity is based on empirical data collected during clinical trials. The activity of the source vial is labeled by the manufacturer as 3.0 GBq±10% and is not independently verified by the end user. This technical note shows that the results of a nondestructive spectroscopic assay of a SIR-Spheres® sample was 26% higher than the activity stated by the manufacturer. This difference should not impact the current empirical prescription method but may be problematic for patient-specific dosimetry applications, such as image-based dosimetry. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00942405
- Volume :
- 35
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Medical Physics
- Publication Type :
- Academic Journal
- Accession number :
- 31521129
- Full Text :
- https://doi.org/10.1118/1.2889621