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Synthesis of RHPS4 via an anionic ring closing cascade
- Source :
-
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry . Apr2008, Vol. 49 Issue 15, p2351-2354. 4p. - Publication Year :
- 2008
-
Abstract
- Abstract: A new and convergent synthesis of the potent telomerase inhibitor RHPS4 is presented. The key step is the construction of the pentacyclic framework via an anionic ring closing cascade in which two new rings are formed. [Copyright &y& Elsevier]
- Subjects :
- *DNA polymerases
*TELOMERASE
*ZINC enzymes
*TRANSFERASES
Subjects
Details
- Language :
- English
- ISSN :
- 00404039
- Volume :
- 49
- Issue :
- 15
- Database :
- Academic Search Index
- Journal :
- Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 31302973
- Full Text :
- https://doi.org/10.1016/j.tetlet.2008.02.074